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Tris Base/CAS:77-86-1
Chemical Name:Tris Base
Molecular Formula:C4H11NO3
Formula Weight:121.14
CAS No.:77-86-1
Category: Pharmaceutical intermediates
Tris Base Typical Properties
Tris(hydroxymethyl)aminomethane, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
Tris Base Specifications:
| tem | Specifications |
| Content | 99.5%—101.0% |
| Moisture（by karl fischer） | ≤0.3% |
| Insolubles | ≤0.005% |
| PH(5%) | 10.0-11.5 |
| UV Absorbance（290nm,40%） | ≤0.2 |
| UV Absorbance（400nm 40%） | ≤0.2 |
| Heavy metals（as pb） | ≤5ppm |
| Fe | ≤5ppm |
| Cl | ≤3ppm |
Tris Base Application
1, Tris buffer, only nucleic acids and proteins are widely used as solvents.
2, Tris is used for protein crystal growth under different pH conditions.
3, Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers.
4, Tris is a major component of protein electrophoresis buffer.
5, Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates.
6, Tris titrated also used as standard.
Tris Base Packaging and Shipping
Tris Base25kgs per drum
Tris Base Storage
Dry cool place
Other product:Benzoin/CAS:119-53-9